Unified API for ESM3 protein design and AlphaFold structure prediction. Self-hosted, cost-optimized, and LLM-ready.
Claude / LLM Streamlit UI
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MCP Server (Tailscale) Gateway :8000
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ESM3 AlphaFold ESMFold
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SageMaker EC2 SageMaker
(auto-stop after idle)
Dynamic routing to ESM3, AlphaFold, and ESMFold through a single API endpoint with health aggregation and service discovery.
Auto-stop idle endpoints after 30 minutes. Pay ~$1.10/hr only when running. Monthly cost: $15-25 with typical research usage.
MCP server exposes all models as conversational tools. Ask an LLM to predict structures, analyze sequences, and compare results.
All infrastructure runs on private networks. Tailscale VPN for remote access. No public endpoints. Your sequences stay private.
9 CDK stacks: VPC, ECS, SageMaker, ECR, monitoring, budgets. One-command deployment. Infrastructure as code.
200+ tests across unit, integration, CDK snapshot, chaos, and property-based testing. 96%+ coverage target.
Generate novel protein sequences, compute embeddings, and score fitness using Meta's ESM3 model on SageMaker.
High-accuracy 3D protein structure prediction with per-residue confidence scores (pLDDT), batch processing, and sequence analysis.
Single-sequence protein folding in ~2 seconds (vs 10 minutes for AlphaFold). Ideal for large-scale screening before detailed prediction.
Talk to your protein models through any MCP-compatible LLM. No code required.
> Analyze the sequence MKFLILLFNILCLFPVLAADNH and predict its structure
Calling alphafold_analyze...
Length: 22 residues
Molecular weight: 2546.1 Da
Isoelectric point: 7.5
Hydrophobicity: 1.509
Top residues: L=27%, F=14%, I=9%
Calling alphafold_predict...
Structure ID: af-22a7b3
Confidence: 89.2
Average pLDDT: 87.4 (22 residues)